Protection that works
Vaccines that prevent STIs
A few STIs can be blocked before they ever happen. Three vaccines do most of that work, and many clinics give them free or cheap.
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Some STIs are vaccine-preventable
Most STIs have no vaccine, but the ones that do are big: HPV, hepatitis A and B, and mpox. A few shots now close those doors for good.
HPV vaccine
Blocks the HPV types behind most genital warts and most HPV cancers. It is routine for kids at 11 or 12, recommended as catch-up through 26, and available up to 45 if you and a clinician decide it makes sense. Getting it as an adult still helps.
Hepatitis A and B
Both can spread through sex. The hepatitis B vaccine is now recommended for all adults 19 to 59, and many adults missed it as kids. It is easy to check your status and catch up in a couple of visits.
Mpox
Spreads through close skin contact, including sex. The vaccine is two doses, four weeks apart, and is recommended if you were exposed or if your sex life puts you around it, including for many gay and bi men and their partners.
Screening still matters
Vaccinated or not, cervical and anal screening catch cell changes early, when they are easiest to handle. Ask a clinic which screening fits you and how often.
Where to get them
Health departments, sexual health clinics, and many pharmacies. Often free with insurance, and public clinics can usually help without it.